Centers for Research in Emerging Infectious Diseases (CREID) Network Coordination Center (U01 Clinical Trial Not Allowed) | RFA AI 24 016

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The Centers for Research in Emerging Infectious Diseases (CREID) Network Coordination Center (U01, Clinical Trial Not Allowed) is a National Institutes of Health (NIH) cooperative agreement funding opportunity (RFA-AI-24-016) focused on building and sustaining a coordinated research network that can better understand and respond to re-emerging and emerging infectious diseases around the world, especially in regions where outbreaks are most likely to occur. The broader CREID Network is made up of awards funded under this notice along with awards funded under a companion CREID NOFO, with the overall intent of expanding scientific knowledge about outbreak-prone pathogens while also strengthening expertise, operational capacity, and readiness to launch or support outbreak-related research when it is needed.

The core purpose of this particular award is to support a Network Coordination Center (CC) that functions as the connective hub for the CREID Network. Rather than operating as a standalone research center, the Coordination Center is meant to advance, facilitate, and coordinate network-wide activities across both outbreak and non-outbreak periods. In practical terms, the CC is expected to help align the participating CREID centers and key stakeholders around shared priorities, smooth collaboration across sites and disciplines, and ensure the network can pivot quickly when an outbreak occurs. Because this is a cooperative agreement (U01), the work is designed to be collaborative and cooperative with NIH involvement, reflecting an expectation of ongoing coordination, shared decision-making processes, and active stewardship to keep the network functioning as an integrated effort.

The notice emphasizes several major categories of responsibilities for the Coordination Center. On the scientific side, the CC supports coordination of select scientific efforts across the network, helping the centers work in a complementary way and promoting synergy rather than duplication. On the data and resource management side, it is positioned to help organize, manage, and facilitate access to data, materials, and other resources generated by or shared among the network, supporting consistent approaches where appropriate. On the communication side, the CC is expected to strengthen information flow across the network and outward to stakeholders, helping ensure that collaboration remains efficient and that the network can communicate clearly during routine periods and during outbreak responses. Finally, the CC is expected to provide administrative coordination and leadership support that holds the network together operationally, including network-level organizing functions that keep multi-site work moving forward.

This funding opportunity sits within the NIH health research mission area and is listed under CFDA 93.855. It is categorized as discretionary funding using the cooperative agreement instrument. The posted award ceiling is $1,500,000, and the original application due date listed is 2024-06-21. The opportunity was created on 2024-03-27. While the notice does not include the expected number of awards in the excerpt provided, it clearly frames the Coordination Center as a central infrastructure and leadership component for the overall CREID program.

Eligibility is broad and includes many types of domestic and non-domestic organizations. Eligible applicants include state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; non-federally recognized tribal organizations; public housing authorities/Indian housing authorities; nonprofits with and without 501(c)(3) status; for-profit organizations other than small businesses; and small businesses. The notice also explicitly highlights additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, U.S. territories or possessions, regional organizations, Indian/Native American tribal governments other than federally recognized, and non-U.S. entities (foreign organizations). This wide eligibility signals an intent to attract applicants with strong coordination capacity and international or cross-institutional reach, consistent with the global and networked nature of emerging infectious disease threats.

A key administrative constraint in the title is that clinical trials are not allowed under this U01, meaning proposed activities should not include clinical trial conduct as defined by NIH, and the focus should remain on coordination and enabling functions that support the network’s research readiness and collaborative work. Overall, the opportunity is best understood as funding for the operational and strategic backbone of the CREID Network: an entity responsible for keeping multi-center efforts aligned, ensuring data and resources are managed effectively, and enabling rapid, organized research responses during outbreaks while maintaining productive coordination during non-outbreak periods.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Centers for Research in Emerging Infectious Diseases (CREID) Network Coordination Center (U01 Clinical Trial Not Allowed)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.855.
• This funding opportunity was created on 2024-03-27.
• Applicants must submit their applications by 2024-06-21. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $1,500,000.00 in funding.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

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