Opportunity Information: Apply for CDC RFA PS23 2306

The Community-Based Approaches to Reducing Sexually Transmitted Diseases (CARS) grant is a CDC funding opportunity designed to help communities reduce sexually transmitted disease (STD/STI) disparities by using strong community engagement and practical, real-world changes to local systems. It is offered by the Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), specifically within NCHHSTP, and it is issued as a cooperative agreement, meaning recipients can generally expect an active partnership with CDC staff through guidance, collaboration, and technical support rather than a hands-off grant relationship.

This opportunity (Funding Opportunity Number CDC RFA PS23 2306; NOFO CDC-RFA-PS23-0006) supports a three-year project period made up of three 12-month budget periods, with an anticipated start date of September 30, 2023. Applications were originally due June 27, 2023 by 11:59 pm ET. The program anticipated making about 4 awards, with an award ceiling of $325,000. The activity category is health (CFDA 93.977), and the opportunity sits in the discretionary funding category.

At its core, CARS is aimed at advancing health equity by helping recipients work alongside communities to identify barriers that drive STD disparities and then implement structural strategies that make it easier for people to protect their sexual health. Instead of focusing only on individual behavior change, the grant emphasizes changing conditions around people, such as improving access points, strengthening referral pathways, reducing service friction, and building lasting partnerships that make prevention and care more reachable and acceptable. The work is intended to support healthy behaviors, build community-clinical linkages, and strengthen the broader prevention ecosystem in ways that are sustainable beyond the grant period. In addition, the NOFO explicitly encourages leveraging these efforts to support related public health priorities, including STD, HIV, and viral hepatitis prevention and control.

The funded work is organized into five major focus areas. First, recipients are expected to implement community engagement methods to achieve health equity. This includes approaches like community-based participatory research and other engagement models where community members help define priorities, shape strategies, and guide implementation, with the goal of making interventions more culturally grounded and more likely to work in the real conditions people face. Second, recipients must identify and implement systems and environmental change strategies that both promote sexual health and support healthy behaviors, while also improving community-clinical linkages. Practically, this can include strengthening pathways between trusted community settings and clinical services so that people can more easily get screening, treatment, partner services, prevention supplies, or referrals without falling through gaps in the system. Third, the program prioritizes enhancing and sustaining partnerships, recognizing that meaningful STD disparity reduction often depends on coordinated work across public health, community organizations, healthcare providers, schools, social services, and other local institutions. Fourth, recipients are expected to support communication strategies that highlight STD program successes and help bring in additional resources, with an emphasis on strengthening capacity for STI control and prevention and connecting that work to broader infectious disease prevention efforts (including HIV and viral hepatitis). Fifth, recipients must evaluate both the effectiveness of the overall approach and the implementation of interventions, so the field learns what works, under what conditions, and how strategies can be improved or scaled.

Eligibility is broad and includes state, county, city/township, and special district governments; independent school districts; public and private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with and without 501(c)(3) status; for-profit organizations (other than small businesses) as well as small businesses; and other entities as clarified in the NOFO. In short, CDC structured eligibility to allow many types of organizations that have strong community ties, service reach, or implementation capacity to apply, as long as they can carry out the community-engaged, systems-focused work and meet the cooperative agreement requirements.

Overall, CARS is best understood as a community-centered STD disparity reduction initiative that invests in partnerships, local infrastructure, and structural improvements rather than isolated short-term activities. The emphasis on community engagement, system and environmental change, communication that builds support and resources, and rigorous evaluation reflects CDCs intent to generate sustainable improvements in how communities prevent STDs and connect people to timely, effective services.

  • The Department of Health and Human Services, Centers for Disease Control - NCHHSTP in the health sector is offering a public funding opportunity titled "Community-Based Approaches to Reducing Sexually Transmitted Diseases (CARS)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.977.
  • This funding opportunity was created on Apr 28, 2023.
  • Applicants must submit their applications by Jun 27, 2023 Electronically submitted applications must be submitted no later than 1159 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $325,000.00 in funding.
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification), Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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