Opportunity Information: Apply for SP 22 004
The Strategic Prevention Framework-Partnerships for Success (SPF-PFS) grant is a discretionary funding opportunity from the U.S. Department of Health and Human Services, administered through the Substance Abuse and Mental Health Services Administration (SAMHSA). Its core aim is to reduce the onset and escalation of substance misuse and the related harms that come with it, while also strengthening mental health promotion at the state and community level. Rather than focusing on treatment after problems have already become severe, this program emphasizes prevention and early intervention strategies that can reduce risk and build protective factors across communities.
A central feature of SPF-PFS is that it is built around the Strategic Prevention Framework (SPF), which is a community engagement and planning model rooted in public health practice. In practical terms, that means funded efforts are expected to be data-driven, organized, and based on evidence. Grantees are meant to use reliable information, including local, state, and national substance use and public health data, to understand what is happening in their communities, identify which problems are most urgent, and decide where prevention work can have the strongest impact. The program also stresses implementation of evidence-based services, meaning prevention approaches that have credible research support rather than informal or untested activities.
The opportunity specifically targets high-risk, underserved communities and at-risk sub-populations. Applicants and eventual recipients are expected to use data to identify which groups are being disproportionately affected or are more likely to experience harm, and then tailor prevention strategies accordingly. The grant recognizes that substance use trends and drivers differ widely across locations, so local context matters. SPF-PFS supports work that strengthens prevention capacity, meaning it helps states and communities improve their ability to plan, coordinate, deliver, and sustain effective prevention services over time, not just run short-term campaigns.
Substance use concerns named within the program’s scope include underage drinking, marijuana, tobacco and nicotine products (including electronic cigarettes), and highly harmful opioids and heroin. Grantees are expected to select prevention priorities based on the best available data and then design and implement strategies that prevent misuse while promoting mental health and overall well-being among both youth and adults. The emphasis is not only on reducing substance use itself, but also on reducing the related negative outcomes and improving community health conditions that influence risk, such as access to supportive services, community norms, and protective environments.
From an administrative standpoint, this opportunity is listed as Funding Opportunity Number SP 22 004 under CFDA (now Assistance Listing) 93.243, categorized under Health. The funding instrument is a grant, with an award ceiling of $1,250,000, and SAMHSA anticipated making about 12 awards under this announcement. The opportunity was created on April 12, 2022, with an original closing date of June 13, 2022. Eligibility is listed broadly as "Others," with additional eligibility details referenced in the full announcement text, suggesting that applicants may include certain non-standard or specifically defined entities beyond the most common categories.
Overall, SPF-PFS is designed to help communities move from general concern about substance misuse to a structured, measurable prevention approach: identify priority problems using data, focus on underserved and high-risk groups, apply evidence-based prevention strategies, and build lasting prevention infrastructure that supports healthier outcomes across the lifespan.Apply for SP 22 004
- The Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis in the health sector is offering a public funding opportunity titled "Strategic Prevention Framework-Partnerships for Success" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.243.
- This funding opportunity was created on Apr 12, 2022.
- Applicants must submit their applications by Jun 13, 2022. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,250,000.00 in funding.
- The number of recipients for this funding is limited to 12 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
SPF-PFS (Strategic Prevention Framework - Partnerships for Success) Grant FAQs
What is the SPF-PFS grant?
The Strategic Prevention Framework-Partnerships for Success (SPF-PFS) grant is a discretionary funding opportunity from the U.S. Department of Health and Human Services (HHS), administered through the Substance Abuse and Mental Health Services Administration (SAMHSA). It supports prevention-focused efforts intended to reduce the onset and escalation of substance misuse and related harms, while also strengthening mental health promotion at state and community levels.
What is the main goal of SPF-PFS?
The core goal is to prevent substance misuse before it becomes severe by emphasizing prevention and early intervention strategies. The program aims to reduce substance-related harms and improve community conditions that influence risk, while also promoting mental health and overall well-being for both youth and adults.
Is this grant focused on treatment or prevention?
This opportunity emphasizes prevention and early intervention rather than treatment after problems have already become severe. Funded work is expected to reduce risk factors, strengthen protective factors, and improve community prevention capacity over time.
Which federal agencies are involved with this opportunity?
HHS is the federal department associated with the grant, and SAMHSA is the administering agency.
What does "Strategic Prevention Framework (SPF)" mean in this program?
SPF refers to the Strategic Prevention Framework, a community engagement and planning model rooted in public health practice. In practical terms, it means grantees are expected to plan and implement prevention work that is structured, data-driven, organized, and guided by evidence.
What does "data-driven" mean for SPF-PFS applicants or grantees?
Data-driven means using reliable information (including local, state, and national substance use and public health data) to understand community needs, identify urgent problems, determine which groups are most affected, select prevention priorities, and target strategies where they can have the strongest impact.
What are "evidence-based services" in the context of this grant?
Evidence-based services are prevention approaches that have credible research support. The program emphasizes implementing prevention strategies supported by evidence rather than informal or untested activities.
Who is this grant intended to benefit?
SPF-PFS specifically targets high-risk, underserved communities and at-risk sub-populations. Funded efforts are expected to identify disproportionately affected groups using data and tailor prevention strategies to local needs and context.
Which substances are included in the scope of SPF-PFS?
Substance use concerns named within the program scope include underage drinking, marijuana, tobacco and nicotine products (including electronic cigarettes), and opioids and heroin. Grantees are expected to use the best available data to select prevention priorities within this scope.
Does SPF-PFS support mental health promotion as well as substance misuse prevention?
Yes. In addition to reducing substance misuse and related harms, the program aims to strengthen mental health promotion at the state and community level and promote overall well-being.
How does SPF-PFS approach differences between communities?
The opportunity recognizes that substance use trends and drivers differ widely across locations, so local context matters. Grantees are expected to use community-relevant data to define priorities and tailor strategies to the realities of their state or community.
What does it mean to "build prevention capacity" under SPF-PFS?
Building prevention capacity means improving the ability of states and communities to plan, coordinate, deliver, and sustain effective prevention services over time. The emphasis is on strengthening prevention infrastructure, not only running short-term campaigns.
What kinds of outcomes is SPF-PFS trying to improve?
The program focuses on reducing substance use and preventing escalation, reducing related negative outcomes and harms, and improving community health conditions that influence risk. Examples of community conditions mentioned include access to supportive services, community norms, and protective environments.
What is the Funding Opportunity Number for this announcement?
The Funding Opportunity Number listed is SP 22 004.
What is the Assistance Listing (CFDA) number for SPF-PFS?
The CFDA (now called the Assistance Listing) number provided is 93.243.
What category is this funding opportunity listed under?
The opportunity is categorized under Health.
What type of funding instrument is SPF-PFS?
The funding instrument is a grant.
What is the maximum award amount (award ceiling)?
The award ceiling is $1,250,000.
How many awards were anticipated under this announcement?
SAMHSA anticipated making about 12 awards under this announcement.
When was this funding opportunity created?
The opportunity was created on April 12, 2022.
What were the original closing date and timeline information?
The original closing date listed for the announcement was June 13, 2022.
Who is eligible to apply?
Eligibility is listed broadly as "Others," with additional eligibility details referenced in the full announcement text. This suggests eligibility may include specifically defined entities beyond the most common applicant categories, but the exact eligible entity types are not specified in the summary provided.
How should prevention priorities be selected under SPF-PFS?
Prevention priorities are expected to be selected based on the best available data. Grantees should use data to identify the most urgent substance misuse issues and related harms, determine which populations are at greatest risk, and focus resources on strategies likely to have the strongest impact.
What is the overall approach SPF-PFS encourages communities to follow?
The program is designed to help communities move from general concern about substance misuse to a structured, measurable prevention approach: identify priority problems using data, focus on underserved and high-risk groups, apply evidence-based prevention strategies, and build lasting prevention infrastructure that supports healthier outcomes across the lifespan.
Browse more opportunities from the same category: Health
Next opportunity: Office of Postsecondary Education (OPE): Higher Education Programs (HEP): Veterans Upward Bound (VUB) Program, Assistance Listing Number (ALN) 84.047V
Previous opportunity: DRL Reconnecting Cuban Exiles with Cuban Civil Society
Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for SP 22 004
Applicants also applied for:
Applicants who have applied for this opportunity (SP 22 004) also looked into and applied for these:
| Funding Opportunity |
|---|
| State Maternal Health Innovation & Data Capacity Program Apply for HRSA 22 149 Funding Number: HRSA 22 149 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Community Health Worker Training Program (CHWTP) Apply for HRSA 22 124 Funding Number: HRSA 22 124 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Rural Opioid Technical Assistance Regional Centers Apply for TI 22 012 Funding Number: TI 22 012 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $650,000 |
| Addressing Dementia in Indian Country: Models of Care Apply for HHS 2022 IHS ALZ 0001 Funding Number: HHS 2022 IHS ALZ 0001 Agency: Department of Health and Human Services, Indian Health Service Category: Health Funding Amount: $200,000 |
| Ending the HIV/HCV Epidemics in Indian Country Apply for HHS 2022 IHS ETHIC 0001 Funding Number: HHS 2022 IHS ETHIC 0001 Agency: Department of Health and Human Services, Indian Health Service Category: Health Funding Amount: $200,000 |
| Demonstrating Effective Policies To Promote Black Youth Mental Health Apply for MP CPI 22 001 Funding Number: MP CPI 22 001 Agency: Department of Health and Human Services, Office of the Assistant Secretary for Health Category: Health Funding Amount: $400,000 |
| PEPFAR Uganda Community Grants to Combat HIV/AIDS Apply for DOS UGA SMGCG FY23 Funding Number: DOS UGA SMGCG FY23 Agency: Department of State, U.S. Mission to Uganda Category: Health Funding Amount: $15,000 |
| Comprehensive Child Centered Care and Services (C4S) Activity Apply for RFI62122OH002 Funding Number: RFI62122OH002 Agency: Agency for International Development, Tanzania USAID-Dar es Salaam Category: Health Funding Amount: $20,000,000 |
| USAID Enhanced HIV Services for Epidemic Control Apply for 72051722RFA00001 Funding Number: 72051722RFA00001 Agency: Agency for International Development, Dominican Republic USAID-Santo Domingo Category: Health Funding Amount: $19,098,000 |
| Preventing Maternal Mortality: Supporting Maternal Mortality Review Committees Apply for CDC RFA DP22 2211 Funding Number: CDC RFA DP22 2211 Agency: Department of Health and Human Services, Centers for Disease Control - NCCDPHP Category: Health Funding Amount: $600,000 |
| Increasing Uptake of Long-Acting Injectable Antiretrovirals Among People with HIV Apply for HRSA 22 155 Funding Number: HRSA 22 155 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: $1,500,000 |
| Cooperative Agreement for the Center of Excellence for Building Capacity in Nursing Facilities to Care for Residents with Behavioral Health Conditions Apply for SM 22 011 Funding Number: SM 22 011 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $4,962,223 |
| Delta Region Rural Health Workforce Training Program Apply for HRSA 22 164 Funding Number: HRSA 22 164 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: $550,000 |
| Sober Truth on Preventing Underage Drinking Act Grants Apply for SP 22 006 Funding Number: SP 22 006 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $50,000 |
| Rural Behavioral Health Workforce Centers – Northern Border Region Apply for HRSA 22 163 Funding Number: HRSA 22 163 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: $625,000 |
| National Center for Disability, Equity, and Intersectionality Apply for HHS 2022 ACL AOD NCDE 0083 Funding Number: HHS 2022 ACL AOD NCDE 0083 Agency: Department of Health and Human Services, Administration for Community Living Category: Health Funding Amount: $500,000 |
| Tribal Opioid Response Grants Apply for TI 22 006 Funding Number: TI 22 006 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $1,925,000 |
| Tribal Public Health Capacity Building and Quality Improvement Umbrella Cooperative Agreement Apply for CDC RFA OT18 18030501SUPP22 Funding Number: CDC RFA OT18 18030501SUPP22 Agency: Department of Health and Human Services, Centers for Disease Control - OSTLTS Category: Health Funding Amount: Case Dependent |
| Strengthening Public Health Systems and Services through National Partnerships to Improve and Protect the Nation's Health Apply for CDC RFA OT18 18020501SUPP22 Funding Number: CDC RFA OT18 18020501SUPP22 Agency: Department of Health and Human Services, Centers for Disease Control - OSTLTS Category: Health Funding Amount: Case Dependent |
| Improving Maternal Health through Addressing Endometriosis, Fibroids, and/or Polycystic Ovary Syndrome Apply for WH AST 22 001 Funding Number: WH AST 22 001 Agency: Department of Health and Human Services, Office of the Assistant Secretary for Health Category: Health Funding Amount: $300,000 |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Inside Our Applicants Portal
Access Applicants Portal
- Grants Repository - Access current and historic funding opportunities with ease. Thousands of funding opportunities are published every week. We can help you sort through the database and find the eligible ones to apply for.
- Applicant Video Guides - The grant application process can be challenging to follow. We can help you with intuitive video guides to speed up the process and eliminate errors in submissions.
- Grant Proposal Wizard - We have developed a network of private funding organizations and investors across the United States. We can reach out and submit your proposal to these contacts to maximize your chances of getting the funding you need.
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Learn More
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "SP 22 004", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.