Opportunity Information: Apply for RFA OD 18 001
The Tobacco Regulatory Science Small Grant Program for New Investigators (R03 Clinical Trial Optional), listed as RFA-OD-18-001, is a federal grant opportunity designed to help early-career researchers launch independent programs of tobacco regulatory science. It targets new investigators working in biomedical, behavioral, and social science disciplines who are still building their research portfolios and need a smaller, starter-style award to generate early results. The core idea is to fund well-scoped projects that can produce credible preliminary findings and position the investigator to compete for larger, subsequent grants focused on tobacco regulation and public health impact.
This opportunity uses the NIH R03 small grant mechanism, which is meant for compact, clearly defined studies rather than large multi-year research enterprises. The announcement emphasizes several project types that fit the R03 structure: pilot and feasibility studies to test concepts or measures, secondary analyses of existing datasets, small self-contained research projects with limited aims, and work focused on developing research methodology or new research technology. Because it is labeled "Clinical Trial Optional," applicants may propose studies that include a clinical trial component if appropriate, but they are not required to do so. The program’s practical focus is on producing data that can serve as a springboard for future investigator-initiated projects that align with federal tobacco regulatory needs.
A central requirement is that proposed research must address priorities tied directly to the regulatory authority of the Food and Drug Administration (FDA) Center for Tobacco Products (CTP). Those priorities stem from the Family Smoking Prevention and Tobacco Control Act (FSPTCA), Public Law 111-31, which gives FDA authority to regulate the manufacture, distribution, and marketing of tobacco products. In other words, the program is not simply about tobacco use in general; it is about generating evidence that can inform regulatory actions and policy decisions within FDA’s statutory framework. Applicants are encouraged to design studies with a clear line of sight to how findings could influence regulation, such as evidence relevant to product characteristics, consumer behavior, marketing exposure, population impacts, or other factors that matter for protecting public health.
Administratively, the awards are made by the National Institutes of Health (NIH) within the Department of Health and Human Services, but the funding comes from designated FDA CTP resources dedicated to tobacco regulatory science. The announcement highlights an NIH-FDA interagency partnership intended to build and sustain a research ecosystem that produces policy-relevant science under the FSPTCA framework. The expectation is that funded projects will deliver enough preliminary evidence, methods, or tools to justify and strengthen later, larger applications that continue to address FDA’s regulation of tobacco products.
In terms of basic logistics, the opportunity falls under the health funding activity category and is associated with CFDA number 93.077. The award ceiling is listed as $50,000, with an expected total of 8 awards. Eligible applicants are broad and include various levels of government (state, county, city/township, special districts), public and private institutions of higher education, independent school districts, federally recognized tribal governments and other tribal organizations, public housing authorities/Indian housing authorities, nonprofit organizations with or without 501(c)(3) status (excluding higher education institutions in those categories), for-profit organizations other than small businesses, small businesses, and additional entities as allowed under the full eligibility language. The posting lists a creation date of November 20, 2017, and an original closing date of February 13, 2019, indicating the timeframe in which that specific announcement cycle was active.
Overall, this FOA is best understood as a targeted entry point into tobacco regulatory science for new investigators: small-budget, tightly focused projects that produce actionable regulatory evidence or foundational methods, explicitly aligned with FDA CTP priorities under federal law, and structured to help investigators build momentum toward larger, sustained research programs that support tobacco product regulation to protect public health.Apply for RFA OD 18 001
- The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "Tobacco Regulatory Science Small Grant Program for New Investigators (R03 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.077.
- This funding opportunity was created on Nov 20, 2017.
- Applicants must submit their applications by Feb 13, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $50,000.00 in funding.
- The number of recipients for this funding is limited to 8 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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